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28 Myotonic Dystrophy - DM1_edited.jpg

 Zebrafish Model of Gastric Tumor ZFGTA

Larvae are microinjected to xenograft AGS cell line 

Assays

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Phenotype Screening

  1. Area of tumor in mm2

  2. % Food Consumption

  3. Survival Rates

  4. QT Interval Prolongation

  5. % Weight

  6. % Swim Activity

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Relative Gene Expression profile - RT PCR

7. HER2 Expression Fold Change

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ELISA and Serum Biochemistry

8.Custom

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Immunohistochemistry

9.% Vasculopathy

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