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28 Myotonic Dystrophy - DM1_edited.jpg

 Zebrafish Model of Phenylketonuria ZFPKL

Phenotype and genotype selected mutants are inbred to obtain PKU+/-

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Assays

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Phenotype Screening

  1. Anxiety Measure

  2. Aggression Measure

  3. Hyperactivity Measure

  4. Tremor Measure

  5. Skin Slough Area

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Relative Gene Expression profile - RT PCR

6. Custome

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ELISA and Serum Biochemistry

7.Phe in Blood

8.Phe in Brain
9. Relative PAH Activity
10. Dopamine Levels in Brain
11. Serotonin levels in Brain

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Histology

12.Custom

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