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Repeat Time points from same Animal

Drug distribution across plasma, tissue and body fluids over time

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Our Services

1

Dosing Route

  • Oral Solid Pellets / Coated Pellets / liquids / Emulsions

  • Intramuscular

  • Subcutaneous

  • Intraperitoneal

  • Intravitreal

  • Intrathecal injection

  • intracranial

  • Intranasal

  • Intra-articular

  • Water Dissolution

2

Analyte Sources

  • Blood - Repeat measure from the same animal through dorsal aorta draw

  • CSF

  • Organs

  • Regions of organs lobes, ventricles, Cortex, Chambers

  • Regenerative Tissue

  • Thymus, Spleen and Kidney

  • Swim Water

3

PK Assessments

  • Area Under the Curve

  • Drug concentration vs time plot

  • Time to peak drug concentration             

  • Peak serum concentration 

  • Biological half-life

  • Volume Distribution

  • Steady state volume of distribution,

  • Clearance

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