Single Gene Mutation Model
Single gene mutants that replicate sequential pathophysiology can be fished out from our living library or used from our frozen library of zebrafish models
Multigene disorder and infectious disease model
Multigene disorder disease models are constructed through grafts as in the case of oncology. Metabolic models through dietary intervention, lewy body models through induction of exogenous fibrils in an PINK mutant etc..
Target Identification and Validation
Idenify expression fold difference in model vs wild type; overexpress or delete identified targets