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28 Myotonic Dystrophy - DM1_edited.jpg

 Zebrafish Model of Stargardt Macular Degeneration ZFMDL

Phenotype and genotype selected mutants are inbred to obtain ABCA4 -/-

Assays

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Phenotype Screening and Quantification

  1. Latency to Light

  2. Latency to Moving Objects

  3. Vascular Leakage Score

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Relative Gene Expression profile - RT PCR

  4. Inflammatory Profile

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ELISA

  5. Custom

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Histology

  6. Basal linear Deposits

  7. Bruch's membrane Thinning
  8. Photoreceptor Degeneration
  9. Retinal Pigment layer Degeneration

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