“Identify promising candidates,
Ensure fool proof translation”
Z-ePhys
Neuro-Behavioral Toxicity Screening System
The Z-ephys system designed at Pentagrit Zebrafish CRO enables identification of promising candidates early in the discovery pipeline and in fool proof translation to field applications by accurate measure of dose range responses and neurobehavior toxicity under a varying stimuli environment. Compound data generated from Z-ephys can be decoded to establish roles of functional groups.
Z-ePhys Capabilities
Screening capacity
10,000 Compounds per Week
Turnaround time
14 Days
Human Equivalence endpoints
Customise Endpoints as in Targets of Human Pathophysiology
Dosing Methods
Water Dissolution, Electroporation of Large Molecules
Assays
Behavioural Phenotype, Morphological Phenotype, Biochemistry, Expression Profiles
High resolution Assay Window
Measures Target Activity in an assay setup where wild type and model are significantly different
Data capture & archive automation
Unbiased and High Quality In-vivo Data