1. Efficacy Screening in Beta Thalassemia Model


 2. PD-L1 Targeting Challenges; Solutions with Zebafish

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 3. Inflammasome Panel for Drug Multipurposing in Pre-Clinical Development


  1. Balkrishna A, Verma S, Solleti SK, Khandrika L, Varshney A. Calcio-Herbal Medicine Divya-Swasari-Vati Ameliorates SARS-CoV-2 Spike Protein-Induced Pathological Features and Inflammation in Humanized Zebrafish Model by Moderating IL-6 and TNF-α Cytokines. J Inflamm Res. 2020;13:1219-1243

  2. Balkrishna, A.; Solleti, S.K.; Verma, S.; Varshney, A. Application of Humanized Zebrafish Model in the Suppression of SARS-CoV-2 Spike Protein Induced Pathology by Tri-Herbal Medicine Coronil via Cytokine Modulation. Molecules 2020, 25, 5091

  3. Balkrishna, Acharya & Solleti, Siva & Verma, Sudeep & Varshney, Anurag. (2020). Validation of a Novel Zebrafish Model of Dengue Virus (DENV-3) Pathology Using the Pentaherbal Medicine Denguenil Vati. Biomolecules. 10. 971. 10.3390/biom10070971

  4. Balkrishna A, Rustagi Y, Bhattacharya K, Varshney A. Application of Zebrafish Model in the Suppression of Drug-Induced Cardiac Hypertrophy by Traditional Indian Medicine Yogendra Ras. Biomolecules. 2020;10(4):600. Published 2020 Apr 13. doi:10.3390/biom10040600

  5. S, Sivamani & Joseph, Joseph. J & Kar, Bibhas. (2014). Anti-inflammatory activity of Withania somnifera leaf extract in stainless steel implant induced inflammation in adult zebrafish. Journal of Genetic Engineering and Biotechnology. 12. 10.1016/j.jgeb.2014.01.002

  6. S, Sivamani & Joseph, Joseph. J & K, Nishwetha & Kar, Bibhas. (2013). Zebrafish as a model for bioavailability testing of counter drug. International Journal of Drug Development & Research. 5. 159-163

  7. S. Sivamani, B. Joseph, and B. Kar. “ZEBRAFISH: AN EMERGING MODEL SYSTEM FOR DRUG DISCOVERY”. Asian Journal of Pharmaceutical and Clinical Research, Vol. 9, no. 4, July 2016, pp. 11-14, https://innovareacademics.in/journals/index.php/ajpcr/article/view/9861

  8. S, Sivamani & Kar, Bibhas. (2013). Adult zebrafish as a new animal model to study anxiety. Asian Journal of Experimental Biological Sciences. 4. 167-171

  9. S M FMB, Chitra K, Joseph B, Sundararajan R, S H. Gelidiella acerosa inhibits lung cancer proliferation. BMC Complement Altern Med. 2018;18(1):104. Published 2018 Mar 20. doi:10.1186/s12906-018-2165-1

  10. S, Sivamani & Joseph, Joseph. J & Kar, Bibhas. (2013). Zebrafish: An in vivo model for the study of liposome mediated drug delivery.. International Journal of Molecular Genetics. 3. 53-61

  11. Kar, Bibhas & S, Sivamani. (2013). Zebrafish: An in Vivo Model for the Study of Human Diseases. International Journal of Genetics & Genomics. 1. 6-11. 10.11648/j.ijgg.20130101.12