An Improved Method for Quantifying Brain Penetrating Drugs in Zebrafish Models
top of page
Blogs - Thoughts and More
A number of new drugs for neurodegenerative and inflammatory disease focus on target sites primarily within the brain. With human ED50 at...
Nathiya P
Jun 281 min read
Do Exceptional Insecticides Exist?
Neuroactive Insecticide Bioactivity Testing
690
Kalaichitra
Jun 171 min read
What Precedes ALS?
There is a need to understand fundamental mechanisms that leads to dysregulation trigger; which eventually leads up to neurodegeneration....
320
News
Be updated of our latest milestones.
Developing Insecticides that are resistance proof - Whitepaper
October 2024: Pentagrit's Target Variant Model Screening system identifies insecticides that can survive a wide range of insect target mutations.
CML Research Models for Resistance Proof Leukaemia Discovery
10 Oct 2024, A Webcast on real world CML discovery challenges and how Pentagrit addresses them.
Paper Publication
10 Aug 2024: Highlights on Neuroinflammatory zebrafish Models
Measuring Drug Concentrations in the Brain
18 July 2024: A New Method for Quantifying Brain Penetrating Drugs in zebrafish models
Deep Phenotyping Zebrafish Models
16 January 2024: Pentagrit to present "Deep Phenotyping Zebrafish Models of ALS, Parkinson's, Tauopathy and Huntington's" at 2nd ACE DRUG DISCOVERY SUMMIT on 20th - 21st MARCH, 2024 at THE INSURANCE HALL LONDON, UK
Glucocerebrosidase Deficient Model
08 November 2023: Watch out for the release of our glucocerebrosidase deficient model with severe lysosomal storage disruption leading to toxic gain of function.
Rheumatoid Arthritis Research Model Endpoints
04 August 2023:New solutions for Rheumatoid Arthritis drug discovery and solutions in our model
New Assay for ALS Neuronal Response
29 August 2023: Assay for ALS drug discovery candidates - Read more at " A Clinical Biomarker Assay for ALS Drug Screening in zebrafish mode
Neurology Screening Endpoints in Models
15 May 2023: Comparison of windows of screening for Neurology Models in zebrafish.
Cardiotoxicity of drugs - Evaluation with Zebrafish ECG
06 April 2023: "Endpoint Data" Watch out for our upcoming round up of ECG detected Cardiovascular Toxicity in zebrafish
Meet Our Team
Purity, Commitment, Excellence
We are made of individual contributors of exceptional science.
bottom of page