Agrochemicals Efficacy Screening System
Zebrafish models carrying target of interest such as ion channels and transporters, APN, ALP, V-ATPase are screened in a HTS system.
Metadata harmonized to Z-Scores for comparative evaluation and compounds scored on dose effect.
Dendrograms or multifactorial analysis predict rate of resistance.
Overcoming resistance, by finding hard to resist molecules using zebrafish system
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OECD TOXICITY AND NECROPSY
Test No. 203: Fish, Acute Toxicity Test
Test No. 204: Fish, Prolonged Toxicity Test: 14-Day Study
Test No. 210: Fish, Early-life Stage Toxicity Test
Test No. 212: Fish, Short-term Toxicity Test on Embryo and Sac-Fry Stages
Test No. 215: Fish, Juvenile Growth Test
Test No. 230: 21-day Fish Assay
Test No. 229: Fish Short Term Reproduction Assay
Test No. 234: Fish Sexual Development Test
Test No. 236: Fish Embryo Acute Toxicity (FET) Test
Test No. 305: Bioconcentration: Flow-through Fish Test
