Dr. Suriya Kayathri
An Improved Method for Quantifying Brain Penetrating Drugs in Zebrafish Models
A number of new drugs for neurodegenerative and inflammatory disease focus on target sites primarily within the brain. With human ED50 at...
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Nathiya P
Jun 281 min
Do Exceptional Insecticides Exist?
Neuroactive Insecticide Bioactivity Testing
630
Kalaichitra
Jun 171 min
What Precedes ALS?
There is a need to understand fundamental mechanisms that leads to dysregulation trigger; which eventually leads up to neurodegeneration....
310
Kalaichitra
Nov 29, 20231 min
Gene Editing without the worry of Liver Edema – Zebrafish Reproducibility Assay
Gene editing primarily focus on threshold of edited protein as an Index of success rate. However in almost all cases, gene editing is met...
460
Kalaichitra
Oct 10, 20232 min
mRNA Therapeutics Development solutions with Zebrafish
mRNA therapeutic applications are growing, however at the clinical stage, they are facing a similar failure rate as of small molecules !...
360
Kalaichitra
Aug 29, 20231 min
A Clinical Biomarker Assay for ALS Drug Screening in zebrafish model
Key Hallmarks of the Assay: Cortical readings from zebrafish ALS models are generated with the similar sensitivity and readouts as in...
620
Kalaichitra
Aug 4, 20232 min
A thorough solution for Rheumatoid Arthritis Discovery with Zebrafish
Current Clinical Challenges: In progressive Rheumatoid Arthritis (RA) candidates are designed to target inflammatory mediators -...
750
Benin Joseph
Jun 21, 20231 min
Fibrotic Scarring Screening - Zebrafish Phenotype Assay
Fish swim against water current to spawn, feed and to stay within a particular habitat. This natural motion against water current is...
530
Benin Joseph
Jun 4, 20232 min
Lessons from NASH RWE that Pre-Clinical Programs should incorporate
Real word Data points to directions away from monotherapies. From lessons learned, the risk of severe side effects of ppar agonism, such...
460
Kalaichitra
Dec 8, 20222 min
Stargardt Macular Degeneration ABCA4-/- Zebrafish Model
Stargardt Disease Pathology Stargardt disease is an autosomal recessive disease caused by mutations in the ABCA4 gene. ABCA4 are...
300
Benin Joseph
Dec 8, 20223 min
Spinal Muscular Atrophy SMN-/- Zebrafish Model
Spinal Muscular Atrophy - Disease Pathology Spinal Muscular Atrophy (SMA) is a genetic condition where the ubiquitously made protein...
160
Benin Joseph
Dec 8, 20222 min
Anxiety Model of Zebrafish & Behavioral Screening Assays
Anxiety Disorder Pathology Anxiety is a neuropsychiatry condition, that mainly affects emotion. Neurotransmitters and hormones such as...
150
Kalaichitra
Dec 8, 20223 min
Autoimmune Encephalomyelitis Zebrafish Model of Multiple Sclerosis
Multiple Sclerosis - Disease Pathology Multiple sclerosis also called as T cell mediated autoimmune disease, is a condition where the...
300
Benin Joseph
Dec 8, 20223 min
Type II Diabetes Zebrafish Model
Type II Diabetes - Disease Pathology Type II Diabetes is a condition that arises due to an environment of dysregulated glucose and fat...
270
Kalaichitra
Dec 8, 20222 min
Phenylketonuria Zebrafish Model
Phenylketonuria Disease Pathology Phenylketonuria also called PKU, is a rare inherited disorder which is caused by build up of amino acid...
590
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