Pentagrit and Lazarus Biosciences Announce Strategic Collaboration to Revolutionise Pre-Clinical Drug Discovery

CHENNAI, INDIA & DUBLIN, IRELAND — October 6, 2026 — Pentagrit, a premier AAALAC-accredited zebrafish laboratory based in Chennai, India, and Lazarus Biosciences, a leading Ireland-based discovery technology developer specialising in mitochondrial biology, advanced imaging, sensing, and data technologies, today announced a new strategic collaboration.

The partnership bridges Pentagrit’s world-class in vivo zebrafish models with Lazarus Biosciences advanced analytical capabilities. By integrating strong chemistry with cutting-edge sensing technology, the two companies are introducing a complementary suite of discovery services designed to accelerate drug discovery pipelines globally.

"Lazarus Biosciences is an Ireland, EU & UK technology company at the forefront of mitochondrial biology, advanced imaging, sensing, and data technologies. The company develops next-generation chemical assays and digital tools designed to decode complex biological responses and provide deeper insights into mitochondrial function and dysfunction across the drug discovery process."

Over 80% of pre-clinical studies are tailored to evaluate a drug’s mechanism of action.

However, traditional tools are frequently force-fitted, capturing only a narrow window of compound activity. To address this industry-wide limitation, Lazarus Biosciences has leveraged advanced chemistry to develop novel, stackable assays. This methodology provides pharmaceutical developers with massive data sets and the flexibility to evaluate a significantly broader scope of compound activity across multiple therapeutic areas.

New Service outcomes of Collaboration

Full-Stack Discovery Studies: Integrated in vitro and in vivo applications that deliver comprehensive data aggregation on test compound profiles inluding robust mitochondrial assays.
Rapid Zebrafish Screening: Novel, 1-hour screening assays tailored for critical disease areas, including inflammation, oncology, neurodegeneration, sleep, psychology, and renal disease.
Quantum Chemistry Physiology Assays: Advanced quantification of zebrafish physiology utilizing state-of-the-art quantum chemistry.
Clinical-Grade Replication: Exceptional assay options engineered to replicate clinical-grade testing protocols directly within zebrafish models.

Regulatory-Ready Data Packs: High-density data generation complete with comprehensive pathology profiles, formatted specifically for seamless FDA submissions.
Deep Mechanistic Insights: Granular mapping of the mechanism of compound activity, featuring more than 100 touchpoints across the dose-effect relationship.

Under this agreement, Lazarus Biosciences will serve as Pentagrit's local direct liaison, officially representing Pentagrit’s comprehensive portfolio of services. This collaboration will significantly strengthen Pentagrit's local presence and enhance support for customers throughout Europe and the UK.

Through this alliance, Pentagrit and Lazarus Biosciences are set to equip global biotechnology and pharmaceutical firms with the high-resolution data and scalable insights required to bring safer, more effective therapeutics to market faster.

About Pentagrit
Pentagrit is an AAALAC-accredited contract research organisation specialising in zebrafish-based pre-clinical models. Operating out of Chennai, India, Pentagrit provides high-standard in vivo screening solutions to validate drug efficacy and safety profiles for global biomedical innovators.

About Lazarus Biosciences
Headquartered in Ireland, Lazarus Biosciences is a discovery technology developer at the forefront of advanced imaging, sensing, and data technologies. The company designs next-generation chemical assays and digital tools to decode complex biological responses during the drug discovery process.

Media Contact:
Keerthana Rajendran
Business Development
Pentagrit
keerthana@pentagrit.com
pentagrit.com