top of page
Prostate / Genitourinary (GU) Cancers
PTEN - Loss of function , P53 - Toxic gain function and Loss of function

Prostate / Genitourinary (GU) Cancers

  • Genotype

    PTEN , P53 

  • Mechanism

    PTEN - Loss of function , P53 - Toxic gain function and Loss of function

  • Phenotype

    Hypoactivity, Cachexia, Fatigue

  • Biomarker

    PSA, PAP, Androgen Receptor, Cyclin E

  • Gene Expression Markers

    PTEN , TP53 , PI3K, KI67 , CDK4/6, AR/PSA, BCL2 ,VIM, Caspase-3

  • Physiology Changes

    Tumor volume, Metastasis, Genomic instability

  • Histology Grading Endpoint

    Invasive tumor, Irregular and fused glands,Nuclear atypia, Lesions

bottom of page