top of page

Chronic Myeloid Leukemia (CML)

Xenografted K562 Cells 

 Phenotype

  • High blast nos in Peripheral Blood

  • High Blast nos in Bone Marrow

  • Splenomegaly

  • Anaemia

  • Fatigue

  • Behavioural Fever

Histology

  • Complete Blood Count

  • Bone Marrow Biopsy

  • Platelets

  • WBC's

  • Cytogenetics - FISH

Tumor Research Model Services

Biomarkers

  • P210 Transcript

  • IL-10 

  • IL-6

  • NFkB

  • Ceramide

  • Smad-7

  • TGF-β1

  • p53

  • EGFR

Gastric Tumor

Xenografted AGS Cells 

 Phenotype

  • Abdominal Bloating

  • Reduce Feed Cycle

  • Weight Loss

  • Ascites

  • Occasional Loose Stools

  • Touched Evoked Abdominal Writhing

Histology

  • Papillary adenocarcinoma infiltrates

  • Diffuse Intestinal Metaplasia

  • Atrophic Gastritis

  • ​Area of tumor staging

  • Tumor invasion into submucosa.

  • Gland-forming lesion that infiltrates into the lamina propria 

  • Nuclear pleomorphism

  • Signet ring cell carcinoma

  • Differentiation Profile

Tumor Research Model Services

Biomarkers

  • Carcinoembryonic antigen

  • CA19-9

  • HER2

  • Alpha-fetoprotein

  • Pepsinogen I/II

  • Cytokeratin subunit 19 fragment

  • hCG

  • PD-L1

  • Fibroblast Growth Factor Receptor 2 

  • Microsatellite instability

  • Neurotrophic receptor tyrosine kinase

  • MUC5AC

  • AE1

  • CK7 

bottom of page